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Benzodiazepines for Sleep

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March 13, 2025

Benzodiazepines for Sleep: Risks, Benefits, and Safer Alternatives

Medically reviewed by: 

Dr. Shiyan Ooi

School of Medical Sciences, University of Manchester

Benzodiazepines are a class of medications commonly prescribed for anxiety and insomnia. While they can be effective for short-term sleep problems, they come with significant risks, including dependence and withdrawal.

How Benzodiazepines Work

Benzodiazepines, such as Xanax (alprazolam), Ativan (lorazepam), and Valium (diazepam), enhance the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that promotes relaxation and sedation. This mechanism helps individuals fall asleep faster and stay asleep longer (National Institutes of Health).

Benefits of Benzodiazepines for Sleep

When used under medical supervision, benzodiazepines can offer several benefits, including:

  • Fast-acting sedative effects
  • Reduction of anxiety that may interfere with sleep
  • Improved sleep duration

Risks and Side Effects

Despite their effectiveness, benzodiazepines have several risks, such as:

  • Dependence and withdrawal symptoms
  • Memory impairment and cognitive decline
  • Increased risk of falls and fractures, especially in older adults
  • Daytime drowsiness and next-day impairment

Long-term use is discouraged due to these potential risks (FDA).

Safer Alternatives to Benzodiazepines

For those seeking effective sleep treatments without the risks of benzodiazepines, alternative approaches include:

  • Cognitive Behavioral Therapy for Insomnia (CBT-I)
  • Melatonin supplementation for circadian rhythm disorders
  • Relaxation techniques such as mindfulness and meditation

Sleep Reset offers a non-medication approach based on CBT-I principles to help individuals improve their sleep naturally.

Conclusion

Benzodiazepines can be an effective short-term sleep aid but come with significant risks. Exploring safer, long-term alternatives can help individuals achieve better sleep without the dangers associated with dependence and withdrawal.

Dr. Shiyan Ooi

Dr. Shiyan Ooi is a medical doctor with over a decade of experience treating patients with chronic conditions. She graduated from the University of Manchester with a Bachelor of Medicine and Surgery (MBChB UK) and spent several years working at the National Health Service (NHS) in the United Kingdom, several Singapore government hospitals, and private functional medicine hospitals. Dr. Ooi specializes in root cause analysis, addressing hormonal, gut health, and lifestyle factors to treat chronic conditions. Drawing from her own experiences, she is dedicated to empowering others to optimize their health. She loves traveling, exploring nature, and spending quality time with family and friends.